International Conference and Exhibition on Marine Drugs and Natural Products July 25-27, 2016 Melbourne, Australia

Thalles Yuri Loiola Vasconcelos was graduated his Bachelor of Pharmacy, from the Applied Theology Institute (INTA) in 2015. He is the Member of the Academic League of Pharmacology (LACFAR) of INTA Colleges in the period between October 2014 and June 2015. His experience in research areas: Pharmacotechnique, Pharmaceutical Technology and Quality Control for Cosmetics and Pharmaceuticals. Currently, he is a member of Research Group on Nutrition, Chemical Elements and Molecules (NELMOL), and post-graduate student in the course of \'Clinical Pharmacy and Pharmaceutical Care\' in Superior School of Amazon.

Babassu is the generic name given to oil palm trees belonging to the Palmae family and members of Orbignya and Attalea genres. The first genus includes predominantly native species of northern Brazil (Maranhão, Piauí, Pará and Ceará, such as Orbignya phalerata Mart (true babassu). Popular indications of babassu use include the treatment of obesity, colitis, arthritis, leukemia, rheumatism, ulcers, tumors and inflammation of the ovaries and uterus. The capacity for healing wounds by substances present in the fruit babassu demonstrated that the topical use of aqueous mesocarp extract afforded wound healing in rats. The powder Orbignya phalerata is obtained from pith and has some anti-inflammatory and analgesic properties proven. The importance of babassu oil in cosmetics products are due to the presence of compounds such as myristic, palmitic and oleic acids. Babassu oil is an emollient oil that can be used in various formulations for the care of skin and hair. It can be employed in cosmetic formulations, such as face creams, cleansing emulsions and creams for body.

Thalles Yuri Loiola Vasconcelos was graduated his Bachelor of Pharmacy, from the Applied Theology Institute (INTA) in 2015. He is the Member of the Academic League of Pharmacology (LACFAR) of INTA Colleges in the period between October 2014 and June 2015. His experience in research areas: Pharmacotechnique, Pharmaceutical Technology and Quality Control for Cosmetics and Pharmaceuticals. Currently, he is a member of Research Group on Nutrition, Chemical Elements and Molecules (NELMOL), and post-graduate student in the course of \'Clinical Pharmacy and Pharmaceutical Care\' in Superior School of Amazon.

Moringa (Moringa oleifera) is a widely adapted plant, that use as a medicinal herb is already recorded since 2000 years B.C. The Moringa oleifera is a natural plant of the Indian northwest, widely distributed not only in India but in the Philippines, Egypt, Thailand, Ceylon, Burma, Malaysia, Singapore, Pakistan, Nigeria and Jamaica. Moringa is a plant having potential for producing various products for topical application. This species has antimicrobial activity against several human pathogens, including gram-negative: Shigella shinga, Pseudomonas aeruginosa, S. sonnei and Pseudomonas spp. And also against gram-positive: Staphylococcus aureus, Bacillus cereus, B-hemolytic streptococcus, Bacillus subtilis, Sarcina lutea and Bacillus megaterium. This effect can be observed in different parts of the plant such as leaves, flowers, seeds, roots and fruit peel. In addition to the bactericidal effect, the aqueous extract of leaves of Moringa oleifera has anti-inflammatory, analgesic, rejuvenating and antioxidant activity. The extract of pulp and seeds of Moringa has healing action, activity attributed to the high content of protein, zinc and anti-microbial components present in Moringa. The healing activity of Moringa oleifera is able to overcome the healing suppression action of dexamethasone. Moringa seeds also have photoprotective activity, being considered an active sunscreen that can be incorporated into other formulations to provide an increase in photoprotection. The presence of flavonoids in Moringa oleifera is reason to encourage researchers to evaluate their potential sunscreen. Thus, several topical formulations can be prepared from the Moringa oleifera as ointments and creams with anti-inflammatory, healing, antimicrobial and even cosmetics with sunscreen and rejuvenating action.

Dr. Garima Pandey has completed her PhD from the University of Lucknow and is presently working as a Research Associate at CSIR-National Botanical Research Institute, Lucknow. She has an extensive work experience in the field of traditional medicine with major focus on integration of traditional knowledge with state of the art science. She has 23 papers published in journals of repute and has a patent filed to her name. She has won various awards; best speaker at conference organized by Association of Ayurvedic Practioners of North America and Best Poster Award at the International Conference on Medicinal Plants, organized by CSIR-CIMAP,rn rnto name a few. She is an active member of the International Society of Ethnobiology and holds a position in the editorial board of two reputed journals in the field of pharmaceutical science.

The Tharu and Buxa tribes of Udham Singh Nagar, Uttarakhand, (India) use grilled fruits of Terminalia bellerica as an effective cure for diarrhea and stomach ulcers. We compared the antidiarrheal effect of grilled fruits (GF) with dried fruits (DF). Total phenol , flavonoid and tannin content was 122.22 mg GAE/g , 47.2mg QE/g and 28.5 mg GAE/ g in DF while 164.30 mg GAE/ g , 57.2 mg QE/g and 46.3 mg GAE/g sample in GF respectively. A 50% ethanolic extract of DF and GF was fractionated and ethyl acetate fractions showed potential DPPH free radical scavenging (IC50 11.13µg/ml in DF and 8.56µg/ml in GF), anti-lipid peroxidation and antibacterial activity. The non-targeted metabolic profiling showed higher content of tartaric acid, valeric acid, succinic acid, oxalic acid, malonic acid, malic acid, 1,2,3 trisbenzene, uridine and 11-eicosenoic acid in GF. The chromatographic studies confermed that gallic acid content was 2.8 (± 0.14) and 4.92 (±0.28) mg/g while ellagic acid content was 4.7 (±0.32) and 4.45 (±0.45) mg/g dry powder in DF and GF respectively. In vivo antidiarrheal activity showed that DF and GF (100 mg/kg oral) inhibited diarrhea by 41.87% and 71.72% respectively. In aspirin induced, pylorus ligation induced and ethanol induced ulcer models, GF showed significant ulcer inhibition (p<0.05-0.001). There was an increase in anti-inflammatory cytokine IL-10 and reduction in pro-inflammatory cytokines TNFα and IL-6 concentration in rats treated with GF and DF. The study indicated that grilling significantly altered the levels of metabolites in T. bellerica fruits which could be responsible for increased therapeutic potential of GF.

Vasileva Elena is a graduate student in the Laboratory of Natural Quinonoid Compounds of G. B. Elyakov Pacific Institute of Bioorganic Chemistry (Vladivostok, Russia).

The coelomic fluid of the sea urchin contains cells, generically called coelomocytes, that have been studied for many decades. Due to their capability to respond to injuries, host invasion, and cytotoxic agents, coelomocytes are regarded as the immune effectors of the sea urchin. One of the subpopulations of coelomocytes are spherical cells with red cytoplasmic granules. In 1885 MacMunn isolated the red pigment from the ceolomic fluid of Echinus esculentus and called it echinochrome A. Since that there is an opinion, that ceolomic fluid of sea urchins contains echinochrome A regardless from their species. We investigated for the first time the composition of quinonoid pigments from ceolomic fluid of eight sea urchin species of the Sea of Japan and the Sea of Okhotsk (Strongylocentrotus intermedius, St. pallidus, St. droebachiensis, St. polyacanthus, Mesocentrotus nudus, Echinocardium cordatum, Scaphechinus mirabilis, Echinarachnius parma) using HPLC-DAD-MS. We discovered that composition of ceolomic fluid pigments differs between the species and includes all known naphthoquinones of sea urchins (echinochrome A, spinochromes A-E, binaphthoquinones) and some new compounds. Main ceolomic fluid pigments were isolated previously from shells and spines of sea urchins M. nudus and Sc. mirabilis and were tested for their ability to scavenge the stable DPPH radical and to inhibit lipid peroxidation. Echinochrome A, spinochromes C and E showed the highest antioxidant activity on both models.rnThe study of antioxidant activity of quinonoid pigments was supported by the Grant No. 16-33-00297 mol_a from Russian Foundation for Basic Research.