Bioactive Natural Products

Natural Products are the source of numerous pharmaceutical and agrochemical agents, and it is reasonable to believe that there are additional agents in existence that remain undiscovered. These natural products are probably defence chemicals targeting and inhibiting the cell division processes of invading plant pathogens. The biofuels produced from the renewable resources could help to minimize the fossil fuel burning and CO2 production. Biofuels produced from biomass such as plants or organic waste could help to reduce both the world’s dependence on oil and CO2 production. These biofuels have the potential to cut CO2 emission because the plants they are made from use CO2 as they grow. Biofuels and bioproducts produced from plant biomass would mitigate global warming. This may due to the CO2 released in burning equals the CO2 tied up by the plant during photosynthesis and thus does not increase the net CO2 in the atmosphere.

Many drugs used today are from plants or are derived from plants. Approx. one-half of all licensed drugs that we were registered worldwide in the 25y period prior to 2007 were natural products or their synthetic derivatives. A review article on the sources of new drugs about 30 year period from 1981 to 2010 shows that a large percentage came from natural sources. It was also reported that among 19 natural product based drugs which were approved for marketing worldwide in between the year 2005 to April 2010, seven were classified as natural products, 10 semi-synthetic natural products and 2 natural product-derived drugs.

  • Modern synthetic agrochemicals
  • Synthesis of enantiopure alkaloid
  • Novel steroid alkaloids
  • Formation of iminium salt
  • Natural products as biofuels and bio-based chemicals

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