Aderanti Oluwaseun Hefsiba
University of Ibadan, Nigeria
Title: Bioactive properties of Murraya paniculata Linn Jack plant
Biography
Biography: Aderanti Oluwaseun Hefsiba
Abstract
Muraya paniculata is grown in Nigeria for aesthetics whereas, the medicinal value of the plant is yet to be exploited. It has been shown that the plant possess many medicinal uses. This study was designed to determine the bioactive properties of M. paniculata plant. Leaves bark and roots were collected from a single home grown tree at University of Ibadan. Samples were washed, air dried for 60days and ground into powdery form. From each component part, 100g of the powdered sample was extracted in 500mL of ethanol for 24 hours and allowed to stand at room temperature. Supernatant was carefully decanted, filtered and evaporated over water bath at 60ºC. Solid extract obtained was used for yield determination of bioactive substances, phyto-chemical analysis and FT-IR. Inhibitory zones of ethanolic extract and ampicillin was compared using clinical isolates of Escherichia coli and Staphylococcus aureus. Experimental design used was CRD. Data were subjected to descriptive statistics and ANOVA at α.05. Yield of bioactive compounds significantly differ from each other with leaves having 62.2%, bark 74.6% and root 67.6%, respectively. Tannin (0.050±0.001%) and cardiac glycosides (0.2103±0.001%) occurred only in the bark. Extracts from bark (27±0.58%), leaves (22.33±0.67%) and root (17±1.15%) significantly inhibited the growth of S. aureus and E. coli compared to that of Ampicillin (17±0.58%), (16±0.58%) and (16.33±0.33%). Chemical groups in the plant parts among others were alcohol, alkene, carboxylic acid and in different wavelengths. Bioactive substances were more in the bark and more effective in inhibiting the growth of tested bacteria.