Natural Products and Medicinal Plants Research

Biography

Biography: Albandary Ziyad

Abstract

Preliminary experiment monitored by ¹H-NMR and HSQC NMR, Myrosinase catalyzed hydrolysis of a glucosinolate (Sinigrin) in the presence of allicin has revealed early evidence of novel compound formation. Both alliins and cruciferous vegetables are known to generate thiol-reactive secondary metabolites when the plant material is crushed. In cruciferous vegetables, these are glucosinolates which degradation into reactive intermediates catalyzed by myrosinase. Garlic, alliinase catalysis conversion of alliin into allicin. Both sets of molecules are known for their antibacterial activity. The aim of this project is to explore where these reactive intermediates could be used to generate novel antimicrobial natural products when if both cruciferous and alliin plants are crushed and extracted as a mixture.