Natural Products Drug Discovery
Natural products have been a rich source of compounds for drug discovery. Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. An integrative approach by combining the various discovery tools and the new discipline of integrative biology will surely provide the key for success in natural product drug discovery and development. Natural products can be predicted to remain an essential component in the search and development for new, safe and economical medicaments. Pharmaceutical industry must awaken in this case to change its mindset and reorient its resources towards the natural product-based drug discovery programs.
Natural products and their derivatives have long been of interest in the fields of chemistry, biology, and medicine because of their unique structural diversity, numerous biological activity, and medicinal properties. Natural product based drug discovery and development is a highly integrated multidisciplinary approach. A significant fraction of the drugs are either natural products or are derived from natural products. Natural products represent a unique and rich source of therapeutic agents and lead structures for new drug discovery.
- Synthesis and isolation of natural products
- Pharmacology, metabolism and toxicology of natural products
- Latest technology in natural products related research
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